Amyloid precursor protein (APP)
Amyloid precursor protein (APP) is a single transmembrane protein that is widely existed in systemic tissue cells. After protease cleavage, it will produce coprotein, which has a toxic effect. So far, people still know little about the real physiological function of APP.
Recently, a team of researchers at the national institute of neuroscience (NNI) has discovered a new function for amyloid precursor protein (APP), one of the leading causes of alzheimer's disease. The discovery could help researchers understand how the protein went wrong in the brains of alzheimer's patients and potentially pave the way for developing innovative therapies to improve brain function in alzheimer's patients.
Zeng Li, the lead author of the study, said that while the exact cause of alzheimer's disease is not known, one of its pathological features is the clear accumulation of apps in the brain.Knowing more about apps could help researchers better understand the disease and potentially identify biomarkers and therapeutic targets. Until now, however, few have understood the main functions of apps in the brain.
New research finds that apps control the growth and maturation of brain cells. In the study, Zeng and her team found that apps can control the growth and maturation of newborn brain cells, which are crucial to maintaining healthy brain function. The APP realizes the above functions by adjusting microrna-574-5-p. MicroRNA is a small molecule that affects human gene expression. The study identified microrna-574-5p promotes the generation of new neurons in the brain. In turn, apps antagonise this process to ensure that new neurons born immediately can support normal brain function. In other words, apps control the growth and maturation of brain cells, without which neuronal expression can be unregulated, causing brain activity to go haywire.
At present, DLDEVELOP co. LTD has developed corresponding APP Elisa products. To get more information, you could contact our professional staff directly or directly to our website:
https://dldevelop.com/Research-reagent/dl-app-mu.html
https://dldevelop.com/Research-reagent/dl-app-ra.html
https://dldevelop.com/Research-reagent/dl-app-hu.html
Recently, a team of researchers at the national institute of neuroscience (NNI) has discovered a new function for amyloid precursor protein (APP), one of the leading causes of alzheimer's disease. The discovery could help researchers understand how the protein went wrong in the brains of alzheimer's patients and potentially pave the way for developing innovative therapies to improve brain function in alzheimer's patients.
Zeng Li, the lead author of the study, said that while the exact cause of alzheimer's disease is not known, one of its pathological features is the clear accumulation of apps in the brain.Knowing more about apps could help researchers better understand the disease and potentially identify biomarkers and therapeutic targets. Until now, however, few have understood the main functions of apps in the brain.
New research finds that apps control the growth and maturation of brain cells. In the study, Zeng and her team found that apps can control the growth and maturation of newborn brain cells, which are crucial to maintaining healthy brain function. The APP realizes the above functions by adjusting microrna-574-5-p. MicroRNA is a small molecule that affects human gene expression. The study identified microrna-574-5p promotes the generation of new neurons in the brain. In turn, apps antagonise this process to ensure that new neurons born immediately can support normal brain function. In other words, apps control the growth and maturation of brain cells, without which neuronal expression can be unregulated, causing brain activity to go haywire.
At present, DLDEVELOP co. LTD has developed corresponding APP Elisa products. To get more information, you could contact our professional staff directly or directly to our website:
https://dldevelop.com/Research-reagent/dl-app-mu.html
https://dldevelop.com/Research-reagent/dl-app-ra.html
https://dldevelop.com/Research-reagent/dl-app-hu.html
